Contributions of the thalamocortical system towards sound-specific auditory plasticity

  title={Contributions of the thalamocortical system towards sound-specific auditory plasticity},
  author={Xiuping Liu and Sidhesh Basavaraj and Ramya Krishnan and Jun Yan},
  journal={Neuroscience \& Biobehavioral Reviews},

Sound‐specific plasticity in the primary auditory cortex as induced by the cholinergic pedunculopontine tegmental nucleus

This study confirms the involvement of the pedunculopontine tegmental nucleus in the plasticity of the auditory cortex in mice and suggests that the PPTg significantly contributes to auditory cortical plasticity via the auditory thalamus and cholinergic basal forebrain.

Thalamic Activation Modulates the Responses of Neurons in Rat Primary Auditory Cortex: An In Vivo Intracellular Recording Study

The cellular mechanism of the cortical activity was investigated, adopting an in vivo intracellular recording technique, and it was found that low-frequency stimuli enhanced the amplitudes of sound-evoked excitatory postsynaptic potentials in AI neurons, whereas high- frequencies depressed these auditory responses.

Thalamic gating contributes to forward suppression in the auditory cortex

It is suggested that the complete suppression that occurs in the thalamus provides the cortex with a “silence” window that could potentially benefit cortical processing and/or perception of the information carried by the preceding sound.

Physiological correspondence dictates cortical long-term potentiation and depression by thalamic induction.

It is shown that conventional high-frequency tetanic stimulation of the auditory thalamus induced long-term changes in cortical field excitatory postsynaptic potentials, including both LTP and LTD, in mice, and the frequency-specificity of cortical LTP/LTD was in accordance with thefrequency-specific plasticity of spike-based RFs of cortical neurons.

Attention and Dynamic, Task-Related Receptive Field Plasticity in Adult Auditory Cortex

The brain is an extraordinarily adaptive and predictive machine, adapting to present demands and predicting the future, and reveals tremendous plasticity in multiple diverse forms, from birth through

Anatomy of the auditory thalamocortical system in the mongolian gerbil: Nuclear origins and cortical field‐, layer‐, and frequency‐specificities

The distinctive layer‐specific distribution of axonal endings within the AC indicates that each of the TC connectivity systems has a specific function in auditory cortical processing.

Imbalance of excitation and inhibition at threshold level in the auditory cortex

The data suggest that the excitatory and inhibitory inputs to single cortical neurons are imbalanced at the threshold level, which may result from the inherent dynamics of thalamocortical feedforward microcircuitry.



The neurobiology of sound-specific auditory plasticity: A core neural circuit

Multiparametric changes in the receptive field of cortical auditory neurons induced by thalamic activation in the mouse.

It is shown here that the neuronal receptive field in the auditory cortex faithfully tends toward the RF of the electrically stimulated auditory thalamic neurons, suggesting that the thalamocortical system possesses intrinsic mechanisms that underlie the input specificity of learning-induced or experience-dependent cortical plasticity.

Augmentation of plasticity of the central auditory system by the basal forebrain and/or somatosensory cortex.

In adult big brown bats, the hypothesis that the AC and corticofugal system play an important role in evoking auditory collicular and cortical plasticity and that auditory and somatosensory signals from the cerebral cortex to the basal forebrain play anImportant role in augmentingcollicular and cortex plasticity is supported.

Cross-Modal Reorganization of Horizontal Connectivity in Auditory Cortex without Altering Thalamocortical Projections

It is shown that early visual inputs to auditory thalamus can reorganize horizontal connections in AI, causing both an increase in their extent and a change in pattern, so that projections are not restricted to the isofrequency axis, but extend in a more isotropic pattern around the injection site.

Sound‐guided shaping of the receptive field in the mouse auditory cortex by basal forebrain activation

All of the effects evoked by basal forebrain activation could be eliminated by cortical application of atropine, the acetylcholine muscarinic receptor antagonist, and the data suggest that cortical plasticity is guided by both sound frequency and amplitude.

Cholinergic modulation incorporated with a tone presentation induces frequency‐specific threshold decreases in the auditory cortex of the mouse

The data suggest that cortical acetylcholine specifically facilitates thalamocortical circuitry tuned to the frequency of a presented tone is the first, fundamental step towards frequency‐specific cortical plasticity evoked by auditory learning and experience.

Learning to hear: plasticity of auditory cortical processing

Disruption of primary auditory cortex by synchronous auditory inputs during a critical period

In the primary auditory cortex (AI), the development of tone frequency selectivity and tonotopic organization is influenced by patterns of neural activity. Introduction of synchronous inputs into the