Contributions of central and peripheral chemoreceptors to the ventilatory response to CO2/H+.

@article{Forster2010ContributionsOC,
  title={Contributions of central and peripheral chemoreceptors to the ventilatory response to CO2/H+.},
  author={H. Forster and C. Smith},
  journal={Journal of applied physiology},
  year={2010},
  volume={108 4},
  pages={
          989-94
        }
}
  • H. Forster, C. Smith
  • Published 2010
  • Biology, Medicine
  • Journal of applied physiology
  • The major objective of this review is to evaluate existing information and reach conclusions regarding whether there is interaction between P(CO(2))/H(+) stimulation of carotid (peripheral) and intracranial (central) chemoreceptors. Interaction is defined as a ventilatory response to simultaneous changes in the degree of Pco2/H(+) stimulation of both chemoreceptors that is greater (hyperadditive) or less (hypoadditive) than the sum of the responses when stimulation of each set of chemoreceptors… CONTINUE READING
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    References

    SHOWING 1-10 OF 66 REFERENCES
    Nature of the interaction between central and peripheral chemoreceptor drives in human subjects.
    • 40
    Response time and sensitivity of the ventilatory response to CO2 in unanesthetized intact dogs: central vs. peripheral chemoreceptors.
    • 149
    • PDF
    Evidence for interaction between the contributions to ventilation from the central and peripheral chemoreceptors in man.
    • P. Robbins
    • Chemistry, Medicine
    • The Journal of physiology
    • 1988
    • 49
    Central-peripheral chemoreceptor ventilatory interaction in awake goats.
    • 25
    Central-peripheral chemoreceptor interaction in awake cerebrospinal fluid-perfused goats.
    • 29
    Brainstem PCO2 modulates phrenic responses to specific carotid body hypoxia in an in situ dual perfused rat preparation
    • 55
    The carotid chemoreceptors are a major determinant of ventilatory CO2 sensitivity and of PaCO2 during eupneic breathing.
    • 39