Contributions of carnitine acetyltransferases to intracellular acetyl unit transport in Candida albicans.

@article{Strijbis2010ContributionsOC,
  title={Contributions of carnitine acetyltransferases to intracellular acetyl unit transport in Candida albicans.},
  author={Karin Strijbis and Carlo W T van Roermund and Janny van den Burg and Marlene van den Berg and Guy P. M. A. Hardy and Ronald Wanders and B. Distel},
  journal={The Journal of biological chemistry},
  year={2010},
  volume={285 32},
  pages={24335-46}
}
Transport of acetyl-CoA between intracellular compartments is mediated by carnitine acetyltransferases (Cats) that reversibly link acetyl units to the carrier molecule carnitine. The genome of the opportunistic pathogenic yeast Candida albicans encodes several (putative) Cats: the peroxisomal and mitochondrial Cat2 isoenzymes encoded by a single gene and the carnitine acetyltransferase homologs Yat1 and Yat2. To determine the contributions of the individual Cats, various carnitine… CONTINUE READING