Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1.

@article{Morrison1997ContributionsOA,
  title={Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1.},
  author={Lynda A Morrison and David Michael Knipe},
  journal={Virology},
  year={1997},
  volume={239 2},
  pages={315-26}
}
Replication-defective mutants of herpes simplex virus 1 (HSV-1) elicit immune responses in mice that reduce acute and latent infection after corneal challenge and are protective against development of disease. To understand the basis for the protective immunity induced by this new form of immunization, we investigated the contribution of various components of the immune response to protection against corneal infection and disease. Passive transfer of sera from mice immunized with the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

The Mouse Brain

Neurobiology of Disease • 2008
View 2 Excerpts

Effect of supplementation with Enterococcus faecium (SF68) on immune functions in cats.

Veterinary therapeutics : research in applied veterinary medicine • 2007

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Construction and characterization of a replication-defective HSV-2

X. J. Da Costa, N. Bourne, L. R. Stanberry, D. M. Knipe
Virology • 1997
View 1 Excerpt

Herpes simplex viruses

R. J. Whitley
In ‘‘Virology’’ (B. Fields and D. Knipe, Eds.), • 1996
View 2 Excerpts

Induction of Th 1 - associated immune responses to beta - galactosidase expressed by a replication - defective mutant of herpes simplex virus 1

R. L. Burke
J . Immunol • 1996

Similar Papers

Loading similar papers…