Contributions of androgen and estrogen to fetal programming of ovarian dysfunction

@article{Abbott2006ContributionsOA,
  title={Contributions of androgen and estrogen to fetal programming of ovarian dysfunction},
  author={David H. Abbott and Vasantha Padmanabhan and Daniel A Dumesic},
  journal={Reproductive Biology and Endocrinology},
  year={2006},
  volume={4},
  pages={17 - 17}
}
In female mammals, including humans, deviations from normal androgenic or estrogenic exposure during fetal development are detrimental to subsequent adult ovarian function. Androgen deficiency, without accompanying estrogen deficit, has little apparent impact on ovarian development. Fetal estrogen deficiency, on the other hand, results in impaired oocyte and follicle development, immature and abnormal adult ovaries, and excessive ovarian stimulation from endogenous gonadotropins ultimately… CONTINUE READING
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