Contributions of Two Inducible Forms of Cytochrome P-450 in Rat Liver Microsomes to the Metabolic Activation of Various Chemical

Abstract

Using the liver 9000 x g supernatant fraction of uninduced rats and monospecific antibodies against microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P450 reductase and two inducible forms of cytochrome P-450, PB-P-450 (major cytochrome P-450 component of the liver microsomes of phenobarbital-treated rats) and MC-P-448 (major… (More)

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