Contributions of Myc to tumorigenesis.

@article{Lutz2002ContributionsOM,
  title={Contributions of Myc to tumorigenesis.},
  author={Werner Lutz and Javier Le{\'o}n and Martin Eilers},
  journal={Biochimica et biophysica acta},
  year={2002},
  volume={1602 1},
  pages={
          61-71
        }
}
Despite intensive research, the mechanisms by which deregulation of myc gene expression contributes to tumorigenesis are still not fully resolved and many aspects are still enigmatic. Several recent reviews, including one published in this series a few months ago, have summarized recent progress in our understanding of the biochemistry of Myc proteins [Eisenmann, Genes Dev. (2001) in press; Amati et al., Biochim. Biophys. Acta 1471 (2001) 135-145]. Also, the evidence documenting a central role… CONTINUE READING
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