Contributions of Gaussian curvature and nonconstant lipid volume to protein deformation of lipid bilayers.

@article{Brannigan2007ContributionsOG,
  title={Contributions of Gaussian curvature and nonconstant lipid volume to protein deformation of lipid bilayers.},
  author={Grace Brannigan and Frank L. H. Brown},
  journal={Biophysical journal},
  year={2007},
  volume={92 3},
  pages={864-76}
}
An elastic model for membrane deformations induced by integral membrane proteins is presented. An earlier theory is extended to account for nonvanishing saddle splay modulus within lipid monolayers and perturbations to lipid volume proximal to the protein. Analytical results are derived for the deformation profile surrounding a single cylindrical protein inclusion, which compare favorably to coarse-grained simulations over a range of protein sizes. Numerical results for multi-protein systems… CONTINUE READING

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