Contribution of the pst-phoU operon to cell adherence by atypical enteropathogenic Escherichia coli and virulence of Citrobacter rodentium.

@article{Cheng2009ContributionOT,
  title={Contribution of the pst-phoU operon to cell adherence by atypical enteropathogenic Escherichia coli and virulence of Citrobacter rodentium.},
  author={Catherine Cheng and Sharon M. Tennant and Kristy I Azzopardi and Vicki R. Bennett-Wood and Elizabeth L Hartland and Roy M Robins-Browne and Marija Tauschek},
  journal={Infection and immunity},
  year={2009},
  volume={77 5},
  pages={1936-44}
}
Strains of enteropathogenic Escherichia coli (EPEC) generally employ the adhesins bundle-forming pili (Bfp) and intimin to colonize the intestine. Atypical EPEC strains possess intimin but are negative for Bfp and, yet, are able to cause disease. To identify alternative adhesins to Bfp in atypical EPEC, we constructed a transposon mutant library of atypical EPEC strain E128012 (serotype O114:H2) using TnphoA. Six mutants that had lost the ability to adhere to HEp-2 cells were identified, and in… CONTINUE READING
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Water content of feces collected from the distal colons of mice 7 days after infection with derivatives of C. rodentium Strain Characteristic(s) Water content

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