Contribution of the TRPV1 channel to salt taste quality in mice as assessed by conditioned taste aversion generalization and chorda tympani nerve responses.

@article{Smith2012ContributionOT,
  title={Contribution of the TRPV1 channel to salt taste quality in mice as assessed by conditioned taste aversion generalization and chorda tympani nerve responses.},
  author={Kimberly Renae Smith and Yada Treesukosol and Andrew B. Paedae and Robert J. Contreras and Alan C Spector},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2012},
  volume={303 11},
  pages={
          R1195-205
        }
}
In rodents, at least two transduction mechanisms are involved in salt taste: 1) the sodium-selective epithelial sodium channel, blocked by topical amiloride administration, and 2) one or more amiloride-insensitive cation-nonselective pathways. Whereas electrophysiological evidence from the chorda tympani nerve (CT) has implicated the transient receptor potential vanilloid-1 (TRPV1) channel as a major component of amiloride-insensitive salt taste transduction, behavioral results have provided… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response.

  • American journal of physiology. Gastrointestinal and liver physiology
  • 2013
VIEW 3 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Spices: the savory and beneficial science of pungency.

  • Reviews of physiology, biochemistry and pharmacology
  • 2013
VIEW 2 EXCERPTS
CITES BACKGROUND & RESULTS

References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Anion size modulates salt taste in rats.

  • Journal of neurophysiology
  • 2012
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

An analysis of residual NaCl taste response after amiloride.

  • The American journal of physiology
  • 1988
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice.

  • American journal of physiology. Regulatory, integrative and comparative physiology
  • 2007
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…