Contribution of structural genomics to understanding the biology of Escherichia coli.

@article{Matte2003ContributionOS,
  title={Contribution of structural genomics to understanding the biology of Escherichia coli.},
  author={Allan Matte and J. Sivaraman and Irena Ekiel and Kalle Gehring and Zongchao Jia and Miroslaw Cygler},
  journal={Journal of bacteriology},
  year={2003},
  volume={185 14},
  pages={
          3994-4002
        }
}
Structural genomics efforts worldwide have the goal of determining large numbers of protein structures in order to complement the ever-expanding database of genome sequences. Currently, some 87 bacterial genomes have been sequenced and another 125 are in progress (http://www.ncbi.nlm.nih.gov/PMGifs/Genomes/micr.html). While structural genomics projects worldwide vary in their specific objectives, nearly all have two common themes. One is to develop high-throughput technologies for gene cloning… CONTINUE READING

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