Contribution of sleep research to the development of new antidepressants

  title={Contribution of sleep research to the development of new antidepressants},
  author={Olivier Le Bon},
  booktitle={Dialogues in clinical neuroscience},
Several sleep anomalies are known to accompany depression and other psychiatric disorders, and to be partially modified by drugs efficient on clinical symptoms. Many puzzling theoretical questions remain, even after 30 years of research, because these drugs do not act in a uniform way: some reduce slow-wave sleep while others increase it some prolong rapid-eye movement sleep latency, while others do not. The relationship between insomnia and depression is likely to be a close one, since a large… CONTINUE READING
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