Contribution of proteoglycan osmotic swelling pressure to the compressive properties of articular cartilage.

Abstract

The negatively charged proteoglycans (PG) provide compressive resistance to articular cartilage by means of their fixed charge density (FCD) and high osmotic pressure (π(PG)), and the collagen network (CN) provides the restraining forces to counterbalance π(PG). Our objectives in this work were to: 1), account for collagen intrafibrillar water when… (More)
DOI: 10.1016/j.bpj.2011.07.006

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