Contribution of persistent Na+ current and M-type K+ current to somatic bursting in CA1 pyramidal cells: combined experimental and modeling study.

@article{Golomb2006ContributionOP,
  title={Contribution of persistent Na+ current and M-type K+ current to somatic bursting in CA1 pyramidal cells: combined experimental and modeling study.},
  author={David Golomb and Cuiyong Yue and Yoel Yaari},
  journal={Journal of neurophysiology},
  year={2006},
  volume={96 4},
  pages={
          1912-26
        }
}
The intrinsic firing modes of adult CA1 pyramidal cells vary along a continuum of "burstiness" from regular firing to rhythmic bursting, depending on the ionic composition of the extracellular milieu. Burstiness is low in neurons exposed to a normal extracellular Ca(2+) concentration ([Ca(2+)](o)), but is markedly enhanced by lowering [Ca(2+)](o), although not by blocking Ca(2+) and Ca(2+)-activated K(+) currents. We show, using intracellular recordings, that burstiness in low [Ca(2+)](o… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 87 REFERENCES

Proximal persistent Na+ channels drive spike afterdepolarizations and associated bursting in adult CA1 pyramidal cells.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2005
VIEW 15 EXCERPTS
HIGHLY INFLUENTIAL

Extracellular calcium modulates persistent sodium current-dependent burst-firing in hippocampal pyramidal neurons.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2001
VIEW 19 EXCERPTS
HIGHLY INFLUENTIAL

KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2004
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

Simulating, Analyzing, and Animating Dynamical Systems: A Guide to XPPAUT for Researchers and Students (Software, Environment, Tools)

B. Ermentrout
  • Philadelphia: Society for Industrial and Applied Mathematics,
  • 2002
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Intrinsic and network rhythmogenesis in a reduced traub model for CA3 neurons

  • Journal of Computational Neuroscience
  • 1995
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

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