Contribution of microbial-associated molecules in innate mucosal responses.

@article{Alexopoulou2005ContributionOM,
  title={Contribution of microbial-associated molecules in innate mucosal responses.},
  author={Lena Alexopoulou and Dimitrios Kontoyiannis},
  journal={Cellular and molecular life sciences : CMLS},
  year={2005},
  volume={62 12},
  pages={1349-58}
}
Both innate immunity and mucosal surfaces provide the first line of defence against mucosal infections. Innate immunity is a universal and evolutionarily conserved form of host defence that senses microbial organisms. Recent advances in the field of immunology are due mainly to the discovery of the role of Toll-like receptors (TLRs), which recognize conserved microbial molecules. TLR stimulation induces specific patterns of gene expression that lead to the shaping of innate and adaptive… CONTINUE READING

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