Contribution of microbial-associated molecules in innate mucosal responses.

  title={Contribution of microbial-associated molecules in innate mucosal responses.},
  author={Lena Alexopoulou and Dimitrios Kontoyiannis},
  journal={Cellular and molecular life sciences : CMLS},
  volume={62 12},
Both innate immunity and mucosal surfaces provide the first line of defence against mucosal infections. Innate immunity is a universal and evolutionarily conserved form of host defence that senses microbial organisms. Recent advances in the field of immunology are due mainly to the discovery of the role of Toll-like receptors (TLRs), which recognize conserved microbial molecules. TLR stimulation induces specific patterns of gene expression that lead to the shaping of innate and adaptive… CONTINUE READING


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