Contribution of melanocortin receptor exoloops to Agouti-related protein binding.

@article{Yang1999ContributionOM,
  title={Contribution of melanocortin receptor exoloops to Agouti-related protein binding.},
  author={Yitian Yang and Chris J. Dickinson and Qingling Zeng and Jun You Li and Devon A. Thompson and Ira Gantz},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 20},
  pages={14100-6}
}
Agouti-related protein (AGRP) is an endogenous antagonist of melanocortin action that functions in the hypothalamic control of feeding behavior. Although previous studies have shown that AGRP binds three of the five known subtypes of melanocortin receptor, the receptor domains participating in binding and the molecular interactions involved are presently… CONTINUE READING