Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine.

@article{Anthony2002ContributionOI,
  title={Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine.},
  author={Joshua C. Anthony and Charles H Lang and Stephen J. Crozier and Tracy G Anthony and David A. Maclean and Scot R. Kimball and Leonard S. Jefferson},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2002},
  volume={282 5},
  pages={E1092-101}
}
Enhanced protein synthesis in skeletal muscle after ingestion of a balanced meal in postabsorptive rats is mimicked by oral leucine administration. To assess the contribution of insulin to the protein synthetic response to leucine, food-deprived (18 h) male rats (approximately 200 g) were intravenously administered a primed-constant infusion of somatostatin (60 microg + 3 microg.kg(-1).h(-1)) or vehicle beginning 1 h before administration of leucine (1.35 g L-leucine/kg) or saline (control… CONTINUE READING

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Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine

Charles H. Lang, Stephen J. Crozier, +3 authors Leonard S. Jefferson
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