Contribution of inorganic polyphosphate towards regulation of mitochondrial free calcium.

@article{Solesio2016ContributionOI,
  title={Contribution of inorganic polyphosphate towards regulation of mitochondrial free calcium.},
  author={Mar{\'i}a E Solesio and Lusine Demirkhanyan and Eleonora Zakharian and Evgeny V. Pavlov},
  journal={Biochimica et biophysica acta},
  year={2016},
  volume={1860 6},
  pages={1317-25}
}
BACKGROUND Calcium signaling plays a key role in the regulation of multiple processes in mammalian mitochondria, from cellular bioenergetics to the induction of stress-induced cell death. While the total concentration of calcium inside the mitochondria can increase by several orders of magnitude, the concentration of bioavailable free calcium in mitochondria is maintained within the micromolar range by the mitochondrial calcium buffering system. This calcium buffering system involves the… CONTINUE READING