Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli.

@article{Remold2001ContributionOI,
  title={Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli.},
  author={Susanna K. Remold and Richard E. Lenski},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 20},
  pages={11388-93}
}
Numerous studies have shown genotype-by-environment (GxE) interactions for traits related to organismal fitness. However, the genetic architecture of the interaction is usually unknown because these studies used genotypes that differ from one another by many unknown mutations. These mutations were also present as standing variation in populations and hence had been subject to prior selection. Based on such studies, it is therefore impossible to say what fraction of new, random mutations… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

References

Publications referenced by this paper.
Showing 1-5 of 5 references

Evolution ( Lawrence , Kans

  • H. A. Orr
  • 1998

Genetics and Analysis of Quantitative Traits (Sinauer

  • M. Lynch, B. Walsh
  • 1998

SAS System for Mixed Models (SAS Institute, Cary, NC)

  • R. C. Littell, G. A. Milliken, W. W. Stroup, R. D. Wolfinger
  • 1996

Evolution in Changing Environments (Princeton Univ. Press, Princeton)

  • R. Levins
  • 1968

Similar Papers

Loading similar papers…