Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin.

@article{Warner2016ContributionOH,
  title={Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin.},
  author={Jacob Warner and Esther L Miranda and D R Mcclay},
  journal={Developmental biology},
  year={2016},
  volume={411 2},
  pages={314-324}
}
Most bilaterians exhibit a left-right asymmetric distribution of their internal organs. The sea urchin larva is notable in this regard since most adult structures are generated from left sided embryonic structures. The gene regulatory network governing this larval asymmetry is still a work in progress but involves several conserved signaling pathways including Nodal, and BMP. Here we provide a comprehensive analysis of Hedgehog signaling and it's contribution to left-right asymmetry. We report… CONTINUE READING
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