Contribution of gene loss to the pathogenic evolution of Burkholderia pseudomallei and Burkholderia mallei.

@article{Moore2004ContributionOG,
  title={Contribution of gene loss to the pathogenic evolution of Burkholderia pseudomallei and Burkholderia mallei.},
  author={Richard A. Moore and Shauna Reckseidler-Zenteno and Heenam Stanley Kim and William C. Nierman and Yan Chun Yu and Apichai Tuanyok and Jonathan Warawa and David DeShazer and Donald E. Woods},
  journal={Infection and immunity},
  year={2004},
  volume={72 7},
  pages={4172-87}
}
Burkholderia pseudomallei is the causative agent of melioidosis. Burkholderia thailandensis is a closely related species that can readily utilize l-arabinose as a sole carbon source, whereas B. pseudomallei cannot. We used Tn5-OT182 mutagenesis to isolate an arabinose-negative mutant of B. thailandensis. Sequence analysis of regions flanking the transposon insertion revealed the presence of an arabinose assimilation operon consisting of nine genes. Analysis of the B. pseudomallei chromosome… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 51 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…