Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort.

@article{Black2009ContributionOF,
  title={Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort.},
  author={Stephanie V. Black and Andrei L S Teixeira and Andrew X Loh and Lynne E. Vinall and John W Holloway and Rebecca Hardy and Dallas M Swallow},
  journal={Allergy},
  year={2009},
  volume={64 8},
  pages={1172-8}
}
BACKGROUND Genetic variants of the two adjacent genes, IL13 and IL4 have frequently been reported as being associated with susceptibility to atopy and asthma, both in adults and children, and some studies also suggest association with lung function and chronic obstructive pulmonary disease. METHODS In this study, we examined for the first time the effect of these variants in 2918 adults in a longitudinal birth cohort, the British National Survey of Health and Development, where there are… CONTINUE READING

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