Contribution of dynamic vascular wall thickening to luminal narrowing during coronary arterial constriction.

@article{Macalpin1980ContributionOD,
  title={Contribution of dynamic vascular wall thickening to luminal narrowing during coronary arterial constriction.},
  author={R N Macalpin},
  journal={Circulation},
  year={1980},
  volume={61 2},
  pages={
          296-301
        }
}
Available estimates of the ratio of wall thickness to luminal radius of human coronary arteries and certain geometrical assumptions were used to calculate the amounts of vascular smooth muscle shortening required to produce specific changes in luminal diameter for hypothetical "normal" and stenotic arteries. The results indicate that even modest mural thickening due to disease may act as a "lever" in translating physiologic degrees of medial smooth muscle shortening into critical luminal… CONTINUE READING

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