Contribution of cytokine-induced neutrophil chemoattractant CINC-2 and CINC-3 to neutrophil recruitment in lipopolysaccharide-induced inflammation in rats

@article{Takano2001ContributionOC,
  title={Contribution of cytokine-induced neutrophil chemoattractant CINC-2 and CINC-3 to neutrophil recruitment in lipopolysaccharide-induced inflammation in rats},
  author={Katsuhiko Takano and Hideo Nakagawa},
  journal={Inflammation Research},
  year={2001},
  volume={50},
  pages={503-508}
}
Objective: We have estimated the contribution of three types of cytokine-induced neutrophil chemoattractants (CINC-1, -2 and -3) and rat macrophage inflammatory protein (MIP)-1α to neutrophil recruitment in the air pouch/ lipopolysaccharide (LPS)-induced inflammation in rats.¶Materials and methods: Excess amounts of anti-CINC-2, CINC-3 and MIP-1α antibodies (Abs), together with LPS (1 μg/ml), were injected into the preformed air pouch of rats. Chemokine levels and chemotactic activity in the… CONTINUE READING