Contribution of collagen adhesion receptors to tissue fibrosis

  title={Contribution of collagen adhesion receptors to tissue fibrosis},
  author={Nuno Miranda Coelho and C A McCulloch},
  journal={Cell and Tissue Research},
Fibrosis is the result of a wound-healing response that fails to restore normal tissue structure function. One of the critical hallmarks of fibrosis is disrupted collagen remodeling. In tissue homeostasis, the production, deposition and organization of collagen is balanced by the degradation and remodeling of collagen within the existing matrix. After injury or chronic infection, tissues initiate a wound-healing response that is intended to create a new ECM for restoring tissue structure and… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.


Publications referenced by this paper.
Showing 1-10 of 172 references

Integrin alpha1beta1

  • H Gardner
  • Adv Exp Med Biol
  • 2014
Highly Influential
19 Excerpts

Similar Papers

Loading similar papers…