Contribution of chondroitin-dermatan sulfate-containing proteoglycans to the function of rat mesenteric arteries.

@article{Gandley1997ContributionOC,
  title={Contribution of chondroitin-dermatan sulfate-containing proteoglycans to the function of rat mesenteric arteries.},
  author={Robin E. Gandley and Margaret K McLaughlin and Thomas J. Koob and Sally A. Little and Linda J. McGuffee},
  journal={The American journal of physiology},
  year={1997},
  volume={273 2 Pt 2},
  pages={H952-60}
}
Proteoglycans are an important nonfibrous matrix component of the arterial wall. Direct evidence for their role in resistance-sized arteries is lacking, although they likely have an important role in coordinating and regulating vessel behavior, presumably via interactions of their glycosaminoglycan chains or core proteins with other matrix molecules and/or the smooth muscle cell surface. The purpose of this study was to determine whether the removal of specific glycosaminoglycan chains from… CONTINUE READING

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