Contribution of calcium ion sequestration by polyoxyethylated nonionic surfactants to the enhanced colonic absorption of p-aminobenzoic acid.


Enhanced absorption of p-aminobenzoic acid (PABA) from the colon by polyoxyethylated nonionic surfactants was investigated using an in situ perfusion technique. The order of their absorption-enhancing effect was as follows: polyoxyethylene lauryl ether greater than polyoxyethylene sorbitan fatty acid esters approximately equal to polyoxyethylene fatty acid… (More)


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