Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: from innocent bystander to active participant.

@article{Sartore2001ContributionOA,
  title={Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: from innocent bystander to active participant.},
  author={S Sartore and Angela Chiavegato and E Faggin and R Franch and Massimo Puato and Simonetta Ausoni and Paolo Pauletto},
  journal={Circulation research},
  year={2001},
  volume={89 12},
  pages={1111-21}
}
The adventitial layer surrounding the blood vessels has long been exclusively considered a supporting tissue the main function of which is to provide adequate nourishment to the muscle layers of tunica media. Although functionally interconnected, the adventitial and medial layers are structurally interfaced at the external elastic lamina level, clearly distinguishable at the maturational phase of vascular morphogenesis. Over the last few years the "passive" role that the adventitia seemed to… CONTINUE READING
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