Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae.

@article{Landman2009ContributionOO,
  title={Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae.},
  author={David Landman and Simona Bratu and John Quale},
  journal={Journal of medical microbiology},
  year={2009},
  volume={58 Pt 10},
  pages={
          1303-8
        }
}
  • David Landman, Simona Bratu, John Quale
  • Published in
    Journal of medical…
    2009
  • Biology, Medicine
  • Isolates of Klebsiella pneumoniae harbouring the carbapenemase KPC may have carbapenem MICs that remain in the susceptible range, and may therefore go unrecognized. To understand the mechanisms contributing to the variability in carbapenem MICs, 20 clinical isolates, all belonging to either of two clonal groups of KPC-possessing K. pneumoniae endemic to New York City, were examined. Expression of genes encoding KPC, the porins OmpK35 and OmpK36, and the efflux pump AcrAB was examined by real… CONTINUE READING

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