Corpus ID: 41613114

Contribution of Leptin to Energy Expenditure and Glucose Metabolism in Fasting

  title={Contribution of Leptin to Energy Expenditure and Glucose Metabolism in Fasting},
  author={N. Ueno and A. Asakawa and A. Inui},
Leptin regulates energy homeostasis and is involved in glucose metabolism. It is known that leptin plays an important role in neuroendocrine response to fasting; therefore, the essential role of leptin may be the response to starvation. In this study, we examined the role of leptin in energy expenditure and glucose metabolism in fasting. Methods: C57BL/6 and leptin mutant ob/ob mice were fasted for 48 hours. Oxygen consumption and blood glucose levels were examined before and after fasting… Expand

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