Contribution of GABAergic cortical circuitry in shaping somatosensory evoked scalp responses: specific changes after single-dose administration of tiagabine

@article{Restuccia2002ContributionOG,
  title={Contribution of GABAergic cortical circuitry in shaping somatosensory evoked scalp responses: specific changes after single-dose administration of tiagabine},
  author={Domenico Restuccia and Massimiliano Valeriani and Eugenio Grassi and Giorgio Gentili and François Maugui{\`e}re},
  journal={Clinical Neurophysiology},
  year={2002},
  volume={113},
  pages={656-671}
}
OBJECTIVES To determine whether conventional as well as high-frequency somatosensory evoked potentials (SEPs) to upper limb stimulation are influenced by GABAergic intracortical circuitry. METHODS We recorded SEPs from 6 healthy volunteers before and after a single-oral administration of tiagabine. Conventional low-frequency SEPs have been obtained after stimulation of the median nerve, as well as after stimulation of the first phalanx of the thumb, which selectively involves cutaneous finger… CONTINUE READING

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