Contribution of GABA-A receptors to metaplasticity in the spinal dorsal horn

@article{Mileti2001ContributionOG,
  title={Contribution of GABA-A receptors to metaplasticity in the spinal dorsal horn},
  author={Gordana Ž. Mileti{\'c} and Vjekoslav Mileti{\'c}},
  journal={Pain},
  year={2001},
  volume={90},
  pages={157-162}
}
  • Gordana Ž. Miletić, Vjekoslav Miletić
  • Published in Pain 2001
  • Biology, Medicine
  • Metaplasticity is a higher-order form of synaptic plasticity that is induced by synaptic or cellular activity, which by itself may not produce changes in synaptic strength, but which modifies subsequent changes in synaptic efficacy. In this description of metaplasticity in the spinal dorsal horn, we report that a 50 Hz high-frequency tetanus, previously shown to elicit a potentiation of sciatic-evoked A-fiber spinal dorsal horn potentials, caused a depression when coupled with a more rapid rate… CONTINUE READING

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