Contribution of Depression to Cognitive Impairment and Dementia in Older Adults

@article{Potter2007ContributionOD,
  title={Contribution of Depression to Cognitive Impairment and Dementia in Older Adults},
  author={Guy G. Potter and David C. Steffens},
  journal={The Neurologist},
  year={2007},
  volume={13},
  pages={105-117}
}
Background:The objective of this review is to provide information for clinicians regarding current research and opinions on the association of depression to conditions of cognitive impairment and dementia. We also intend to integrate this current research and thinking into strategies for the assessment and treatment of depression in the context of cognitive impairment. Review Summary:Depression is highly prevalent in mild cognitive impairment and most dementias. It may be a risk factor for the… Expand
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Depression
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With the greater ability to improve the lives of patients with depression, it is important for neurologists to recognize depression and work with psychiatric colleagues to help patients access the newest and best treatments. Expand
Late-life depression, mild cognitive impairment, and dementia: possible continuum?
  • F. Panza, V. Frisardi, +9 authors V. Solfrizzi
  • Psychology, Medicine
  • The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2010
Clinical and epidemiologic research has focused on the identification of risk factors that may be modified in predementia syndromes, at a preclinical and early clinical stage of dementing disorders,Expand
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The reported prevalence of comorbid depression or depressive symptoms in individuals with dementia has been quite variable, likely due to differences in methods of assessment, diagnostic criteria, stages of dementia, and other factors. Expand
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The severity of vascular burden was significantly correlated with depression severity and impaired performance on measures of cognitive control, but not memory or verbal fluency, and the severity of comorbid apathy nor medical illness burden was related to cognitive impairment. Expand
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ACE-R has diagnostic accuracy in detecting people with AD and can be used in differential diagnostics of late-life onset depression (severe episode) and AD. Expand
[Depression and cognitive decline in elderly: causes and consequences].
The authors discuss the relationship between depression and cognitive impairment in the aspect of mechanisms of their development, variants of comorbidity and recommendations on differentiatedExpand
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Multiple factors were found to modulate cognitive performance in dementia-free unipolar old-age depression, and consistent with the notion that depression is a heterogeneous disorder, this may explain why patterns of cognitive deficits in depression vary between studies. Expand
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In elderly individuals, high level of depressive symptoms is predictive of vascular dementia within a few years, and a close temporal association suggests that depression is less a risk factor for than a prodromal symptom ofascular dementia. Expand
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