Contribution of CD8+ T cells to control of Mycobacterium tuberculosis infection.

@article{Sud2006ContributionOC,
  title={Contribution of CD8+ T cells to control of Mycobacterium tuberculosis infection.},
  author={Dhruv Sud and Carolyn L Bigbee and JoAnne L. Flynn and Denise E. Kirschner},
  journal={Journal of immunology},
  year={2006},
  volume={176 7},
  pages={4296-314}
}
Tuberculosis is the number one cause of death due to infectious disease in the world today. Understanding the dynamics of the immune response is crucial to elaborating differences between individuals who contain infection vs those who suffer active disease. Key cells in an adaptive immune response to intracellular pathogens include CD8(+) T cells. Once stimulated, these cells provide a number of different effector functions, each aimed at clearing or containing the pathogen. To explore the role… CONTINUE READING