Contribution of α1 subunit-containing γ-aminobutyric acidA (GABAA) receptors to motor-impairing effects of benzodiazepines in squirrel monkeys

Abstract

Benzodiazepines (BZs) are effective anxiolytics and hypnotics, but their use is limited by unwanted side effects, such as motor impairment. To assess the contribution of α1 subunit-containing γ-aminobutyric acidA (GABAA) receptor subtypes to the motor-impairing effects of BZs, the present study evaluated two observable measures of motor coordination… (More)
DOI: 10.1007/s00213-008-1401-7

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