Contrasting the efficacy of selection on the X and autosomes in Drosophila.

@article{Singh2008ContrastingTE,
  title={Contrasting the efficacy of selection on the X and autosomes in Drosophila.},
  author={Nadia D. Singh and Amanda M Larracuente and Andrew G. Clark},
  journal={Molecular biology and evolution},
  year={2008},
  volume={25 2},
  pages={454-67}
}
To investigate the relative efficacy of both positive and purifying natural selection on the X chromosome and the autosomes in Drosophila, we compared rates and patterns of molecular evolution between these chromosome sets using the newly available alignments of orthologous genes from 12 species. Parameters that may influence the relative X versus autosomal substitution rates include the relative effective population sizes, the male and female germline mutation rates, the distribution of… CONTINUE READING