Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon.

@article{Sousa2000ContrastingSA,
  title={Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon.},
  author={Sara L M de Sousa and Robert Dickinson and William Robert Lieb and Nicholas P Franks},
  journal={Anesthesiology},
  year={2000},
  volume={92 4},
  pages={1055-66}
}
BACKGROUND The mechanisms by which the inhalational general anesthetics isoflurane and xenon exert their effects are unknown. Moreover, there have been surprisingly few quantitative studies of the effects of these agents on central synapses, with virtually no information available regarding the actions of xenon. METHODS The actions of isoflurane and xenon on gamma-aminobutyric acid-mediated (GABAergic) and glutamatergic synapses were investigated using voltage-clamp techniques on autaptic… CONTINUE READING
83 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 83 extracted citations

Similar Papers

Loading similar papers…