Contrasting patterns of nuclear and mtDNA diversity in Native American populations.

  title={Contrasting patterns of nuclear and mtDNA diversity in Native American populations.},
  author={Ning Ning Yang and St{\'e}phane Mazi{\`e}res and Claudio M. Bravi and N. Ray and Sijia Wang and M A Burley and Gabriel Bedoya and Winston Rojas and Mar{\'i}a Victoria Parra and Julio A. Molina and Carla Gallo and Giovanni Poletti and Kim Hill and Ana Magdalena Hurtado and Maria Luiza Petzl-Erler and Luiza Tamie Tsuneto and William J. Klitz and Ramiro Barrantes and Elena R Llop and Francisco Rothhammer and Damian Labuda and Francisco M Salzano and Maria-C{\'a}tira Bortolini and Laurent Excoffier and Jean Michel Dugoujon and Andres Ruiz-Linares},
  journal={Annals of human genetics},
  volume={74 6},
We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration… CONTINUE READING