Contrasting patterns of Y chromosome variation in Ashkenazi Jewish and host non-Jewish European populations

@article{Behar2003ContrastingPO,
  title={Contrasting patterns of Y chromosome variation in Ashkenazi Jewish and host non-Jewish European populations},
  author={Doron M Behar and Daniel Garrigan and Matthew E. Kaplan and Zahra Mobasher and Dror Rosengarten and Tatiana Karafet and Llu{\'i}s Quintana-Murci and Harry Ostrer and Karl Skorecki and Michael F. Hammer},
  journal={Human Genetics},
  year={2003},
  volume={114},
  pages={354-365}
}
The molecular basis of more than 25 genetic diseases has been described in Ashkenazi Jewish populations. Most of these diseases are characterized by one or two major founder mutations that are present in the Ashkenazi population at elevated frequencies. One explanation for this preponderance of recessive diseases is accentuated genetic drift resulting from a series of dispersals to and within Europe, endogamy, and/or recent rapid population growth. However, a clear picture of the manner in… Expand
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