Contrasting pathogenesis of atopic dermatitis and psoriasis—Part I: Clinical and pathologic concepts

@article{GuttmanYassky2011ContrastingPO,
  title={Contrasting pathogenesis of atopic dermatitis and psoriasis—Part I: Clinical and pathologic concepts},
  author={Emma Guttman-Yassky and Kristine E. Nograles and James G. Krueger},
  journal={The Journal of allergy and clinical immunology},
  year={2011},
  volume={127 5},
  pages={1110-8}
}
Atopic dermatitis and psoriasis are 2 of the most common inflammatory skin diseases. They are similar in that they are complex inherited diseases involving genes that encode immune components and structural proteins that regulate differentiation of epidermal cells. Each disease is characterized by proliferation of epidermal keratinocytes and abnormal cornification or terminal differentiation in the epidermis; skin lesions contain immune infiltrates of T cells, dendritic cells, and other types… CONTINUE READING

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