Contrasting effects of verapamil and procainamide on rate-dependent bundle branch block: pharmacologic evidence for the role of depressed sodium channel responses.

@article{Chiale1990ContrastingEO,
  title={Contrasting effects of verapamil and procainamide on rate-dependent bundle branch block: pharmacologic evidence for the role of depressed sodium channel responses.},
  author={Pablo Ambrosio Chiale and J D Pastori and Rub{\'e}n Arg{\"u}ero S{\'a}nchez and Marcelo V{\'i}ctor Elizari and Mauricio Rosenbaum},
  journal={Journal of the American College of Cardiology},
  year={1990},
  volume={15 3},
  pages={633-9}
}
The mechanisms responsible for intermittent bundle branch block are still under debate. The role of the time-dependent behavior of the slow calcium channel has recently been emphasized. To test this hypothesis and ascertain the possible involvement of the fast sodium channel, the effects of the slow calcium channel blocker verapamil and the fast sodium… CONTINUE READING