Contrasting effects of sunitinib within in vivo models of metastasis

Abstract

Sunitinib is a potent and clinically approved tyrosine kinase inhibitor that can suppress tumour growth by inhibiting angiogenesis. However, conflicting data exist regarding the effects of this drug on the growth of metastases in preclinical models. Here we use 4T1 and RENCA tumour cells, which both form lung metastases in Balb/c mice, to re-address the… (More)
DOI: 10.1007/s10456-012-9291-z

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@inproceedings{Welti2012ContrastingEO, title={Contrasting effects of sunitinib within in vivo models of metastasis}, author={Jonathan C. Welti and Thomas Powles and S. M. Foo and Morgane Gourlaouen and Natasha P U Preece and Julie C Foster and Sophia Frentzas and Demelza Bird and Kevin Sharpe and Antoinette van Weverwijk and D. Robertson and Julie Soffe and Janine T Erler and Roberto Pili and Caroline J. Springer and Stephen John Mather and Andrew Reynolds}, booktitle={Angiogenesis}, year={2012} }