Contrasting effects of captopril and nifedipine in normotensive patients with incipient diabetic nephropathy.

@article{Mimran1988ContrastingEO,
  title={Contrasting effects of captopril and nifedipine in normotensive patients with incipient diabetic nephropathy.},
  author={Albert Mimran and Ana Mar{\'i}a Insua and Jean Ribstein and Louis Monnier and Jacques Bringer and Jacques Mirouze},
  journal={Journal of hypertension},
  year={1988},
  volume={6 11},
  pages={919-23}
}
Microalbuminuria is a reliable predictor of the eventual development of overt diabetic nephropathy and blood pressure is known to accelerate the course of this nephropathy. In the present studies, the effect of a 6-week treatment by placebo (n = 7), nifedipine (n = 7) and captopril (n = 8) on renal function and urinary excretion of albumin (UAE) was investigated in normotensive, insulin-dependent, diabetic patients with incipient nephropathy (UAE greater than 15 micrograms/min). No change in… CONTINUE READING

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