Contrasting effects of IL-4, IL-10 and corticosteroids on RANTES production by human monocytes.

Abstract

RANTES is a chemokine produced in delayed-type hypersensitivity (DTH) and allergic reactions, in which it may contribute to the recruitment of immune cells. Macrophages participate in the cellular infiltration in both conditions and they represent a potent source of RANTES. To understand the regulation of RANTES production by human monocytes, we analyzed… (More)

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