Contrast sensitivity loss in multiple sclerosis. Selectivity by eye, orientation, and spatial frequency measured with the evoked potential.

@article{Kupersmith1984ContrastSL,
  title={Contrast sensitivity loss in multiple sclerosis. Selectivity by eye, orientation, and spatial frequency measured with the evoked potential.},
  author={Mark J. Kupersmith and William H. Seiple and J. I. Nelson and Ronald E. Carr},
  journal={Investigative ophthalmology & visual science},
  year={1984},
  volume={25 6},
  pages={632-9}
}
Multiple sclerosis can produce highly selective losses in visual function. Psychophysical studies have demonstrated contrast sensitivity deficits for spatial frequencies or for stimulus orientations. Using real-time lock-in retrieval of the visual evoked potential, the authors measured contrast sensitivity in 15 cases with probable or definite multiple sclerosis and acuities of 20/40 or better. Sine-wave grating contrast threshold determinations for three spatial frequencies (1, 4, and 8 cycles… CONTINUE READING

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