Contrast media hypersensitivity--scope of the problem.

  title={Contrast media hypersensitivity--scope of the problem.},
  author={K Brockow},
  volume={209 2},
Hypersensitivity reactions to contrast media (CM) are frequent causes of anaphylactically induced fatalities. Adverse events after CM exposure are classified into immediate and non-immediate reactions, with differing pathomechanisms. In the majority of patients with immediate reactions, IgE-mediated allergy can not be demonstrated and the underlying mechanism remains unknown. However, recent data has provided evidence for skin test positivity and/or specific IgE in some patients with severe… CONTINUE READING

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