Contrast-enhanced ultrasound measurement of pancreatic blood flow dynamics predicts type 1 diabetes progression in preclinical models

@inproceedings{Clair2018ContrastenhancedUM,
  title={Contrast-enhanced ultrasound measurement of pancreatic blood flow dynamics predicts type 1 diabetes progression in preclinical models},
  author={Joshua R. St. Clair and David B{\'a}ez-L{\'o}pezJuan Manuel Ram{\'i}rez and Samantha Passman and Richard K. P. Benninger},
  booktitle={Nature Communications},
  year={2018}
}
In type 1 diabetes (T1D), immune-cell infiltration into the islets of Langerhans (insulitis) and β-cell decline occurs many years before diabetes clinically presents. Non-invasively detecting insulitis and β-cell decline would allow the diagnosis of eventual diabetes, and provide a means to monitor therapeutic intervention. However, there is a lack of… CONTINUE READING