Contrast-enhanced NMR imaging: animal studies using gadolinium-DTPA complex.

@article{Brasch1984ContrastenhancedNI,
  title={Contrast-enhanced NMR imaging: animal studies using gadolinium-DTPA complex.},
  author={Robert C. Brasch and Hanns Joachim Weinmann and George E. Wesbey},
  journal={AJR. American journal of roentgenology},
  year={1984},
  volume={142 3},
  pages={625-30}
}
Gadolinium (Gd)-DTPA complex was assessed as a nuclear magnetic resonance (NMR) contrast-enhancing agent by experimentally imaging normal and diseased animals. After intravenous injection, Gd-DTPA, a strongly paramagnetic complex by virtue of unpaired electrons, was rapidly excreted into the urine of rats, producing an easily observable contrast enhancement on NMR images in kidney parenchyma and urine. Spin-echo intensity of urine within the renal pelvis increased from 2263 to 4414 units… CONTINUE READING

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