Contraluminal para-aminohippurate (PAH) transport in the proximal tubule of the rat kidney

  title={Contraluminal para-aminohippurate (PAH) transport in the proximal tubule of the rat kidney},
  author={Karl J. Ullrich and Gerhard Rumrich and G{\"u}nter Fritzsch and Stephan Kloess},
  journal={Pfl{\"u}gers Archiv},
In order to study the characteristics of contraluminal para-aminohippurate transport into proximal tubular cells the stopped flow capillary perfusion method was applied. The disappearance of3H-paraaminohippurate from the capillary perfusate at different concentrations and contact times was measured and saturation type behaviour was found with aK m of 0.08±0.01 (SE) mmol/l,J max of 1.1±0.1 pmol·s−1·cm−1 andr, the final extracellular/intracellular distribution ratio of 0.93±0.03. Omission of Na… CONTINUE READING


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Contraluminal paraaminohippurate ( PAH ) transport in the proximal tubule of the rat kidney . II . Specificity : Aliphatic dicarboxylic acids

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