Contraction threshold and the "hump" component of charge movement in frog skeletal muscle

@article{Szcs1991ContractionTA,
  title={Contraction threshold and the "hump" component of charge movement in frog skeletal muscle},
  author={G{\'e}za Sz{\"u}cs and L{\'a}szl{\'o} Csernoch and J{\'a}nos Magyar and L. {\'O}. Kov{\'a}cs},
  journal={The Journal of General Physiology},
  year={1991},
  volume={97},
  pages={897 - 911}
}
The delayed component of intramembranous charge movement (hump, I gamma) was studied around the contraction threshold in cut skeletal muscle fibers of the frog (Rana esculenta) in a single Vaseline-gap voltage clamp. Charges (Q) were computed as 50-ms integrals of the ON (QON) and OFF (QOFF) of the asymmetric currents after subtracting a baseline. The hump appeared in parallel with an excess of QON over QOFF by approximately 2.5 nC/mu F. Caffeine (0.75 mM) not only shifted the contraction… CONTINUE READING